EFFECTIVENESS OF LOW DOSE METHOTREXATE IN GENERALISED
VITILIGO COMPARED TO UVB PHOTOTHERAPY IN PATIENTS
ATTENDING TO DERMATOLOGY CLINIC-TH BADULLA 2022-2023
Gunarathne HWNN 1 , Wannigama E 2 , Iddamalgoda V L 3 ,Jayasinghe P P 3
Edition 01 :Vol 01
JOHAID:2400918-AUD-UBV-JOHA
Abstract
Vitiligo is a chronic skin disorder characterized by the progressive loss of melanocytes,
leading to depigmented patches on the skin. The condition affects individuals of all ages,
races, and genders, resulting in considerable psychosocial and healthcare burdens
worldwide. Though the exact cause remains unclear, vitiligo is believed to involve an
autoimmune mechanism that targets melanocytes, contributing to the visible skin changes.
This disorder is not life-threatening but has a significant impact on the quality of life due to
its effect on appearance and associated stigma.
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